He served as Ecumenical Patriarch during the period of 1863-1866. On 30th May 1870 he was elected Patriarch of Alexandria. In 1888 he established the Holy Church of the Transfiguration of the Saviour in Port Said . His tenure as Patriarch was tainted by the unfair expulsion of the Patriarchal Vicar of Cairo, Metropolitan Nektarios Kephalas of Pentapolis, whom the Chu rch elevated to Sainthood following his death.